A Pilot Study to Examine Efficacy of Peer Mentoring in Promoting Medication Adherence Among People Living With HIV/AIDS

N/AUnknownNCT02025322

Jury Candelario36 enrolled

Overview

This study aims to investigate the effectiveness of an in-person peer mentoring and health literacy intervention on improving medication adherence, HIV-1 viral load, CD4+ T lymphocyte counts, and HIV medical appointment attendance among newly-diagnosed and/or medication non-adherent HIV-positive individuals, compared to standard of care provider/staff-delivered education.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

HIV

Interventions

Peer MentoringBEHAVIORAL

Participants in the Peer Mentoring arm will be paired with a Peer Mentor for the duration of the 4-month intervention. Peer Mentors are HIV-positive patients who demonstrate high levels of medication and treatment adherence and are knowledgeable about HIV/AIDS and barriers to care. During the 4-month intervention, Peer Mentors will contact participants weekly via in-person, phone, or email, with the option to provide more frequent contact, if needed. Peer Mentors will provide social support and remind participants to take their medications and attend upcoming medical appointments. Study participants will also attend four monthly, one hour workshops on HIV/AIDS, medication adherence, health literacy, and health and wellness, which will be developed and co-facilitated by Peer Mentors.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: All of the following criteria must be met for a participant to be eligible for the study: * Confirmed diagnosis of HIV-1 * Newly diagnosed and initiating treatment (e.g., treatment naive) OR off medications for more than fourteen consecutive days (2 weeks) and re-initiating treatment OR currently on antiretroviral therapy with demonstrated ongoing adherence problems (missing more than 3 doses per month) * Has a detectable (greater than 50 copies/ml) HIV-1 viral load * Is able to obtain HIV medications during the entire study period (e.g., if uninsured, is enrolled in AIDS Drug Assistance Program). Exclusion Criteria: Subject is ineligible for this study if: * He/She suffers from cognitive impairment, active psychosis, or has a known history of harming others, OR * He/She has a severe mental health and/or substance abuse condition that requires residential or inpatient treatment, OR * The medical provider believes participation would not be in the best interest of the subject for other reasons.

Locations (1)

APAIT Health Center

Los Angeles, California, United States

Outcomes

Primary Outcomes

Efficacy of Peer Mentoring on Improving Medication Adherence

Test the efficacy of a peer mentoring intervention on improving medication adherence among newly diagnosed and/or medication non-adherent HIV-positive individuals, compared to standard of care.

Time frame: 4 months post-baseline

Secondary Outcomes

Assess the Long-Term Impact of Peer Mentoring on Medication adherence

Assess the long-term impact of peer mentoring on medication adherence among newly diagnosed and/or medication non-adherent HIV-positive individuals, compared to standard of care.

Time frame: 6-months post-baseline

Data from ClinicalTrials.gov

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