The study hypothesized that a relative low oxygen concentration (40%) supplemental would be advantageous to protect the pulmonary function of patients, comparied with conventional high oxygen concentration (80%). Therefore we raise this prospective randomized controlled research.
Patients underwent minimally invasive esophagectomy in Zhongshan Hospital of Fudan University will be enrolled and be randomizedly assigned to low oxygen concentration (40%) supplemental or high oxygen concentration(80%) supplemental group. Intra-operative and post-operative pressure of Oxygen in Arterial Blood will be examined, and the surgical outcome will be recorded in the two groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
120
low supplemental oxygen concentration would be used during the surgery
high supplemental oxygen concentration would be used during the surgery
Division of Thoracic Surgery & Anesthesiology, Zhongshan Hospital of Fudan University
Shanghai, Shanghai Municipality, China
RECRUITINGThe change of oxygenation index
The change of oxygenation index is an important index to indicate the pulmonary function of patients.
Time frame: Change from Baseline at post-operative Day1
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