CCTA-based Coronary Plaque Characterization and High-sensitive Troponin T for the Prediction of Cardiovascular Outcomes

N/ACompletedNCT02030704

University Hospital Heidelberg300 enrolled

Overview

To determine the ability of semi-automated plaque assessment in cardiac computed tomography angiography (CCTA) and high sensitive troponin T (hsTnT) for the risk stratification of patients at intermediate risk for coronary artery disease (CAD).

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Coronary Artery Disease Noninvasive Plaque Characterization

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical indication for CCTA according to the current appropriate use criteria Exclusion Criteria: * non-sinus rhythm * acute coronary syndromes * cardiomyopathies * moderate or severe valvular disease * elevated serum creatinine (\>1.5 mg/dl) * history or ECG signs of previous myocardial infarction * severe iodine allergy.

Locations (2)

University of Heidelberg, Department of Cardiology

Heidelberg, Baden-Wurttemberg, Germany

MTA-SE Lendület Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University

Budapest, Hungary

Outcomes

Primary Outcomes

Cardiac death

Time frame: two years

Nonfatal myocardial infarction

Time frame: two years

Secondary Outcomes

Myocardial revascularization including PCI and CABG

PCI - Percutaneous Coronary Intervention CABG - Coronary Artery Bypass Grafting

Time frame: two years

Data from ClinicalTrials.gov

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