Ph2a Study to Evaluate IW-3718 in Patients With Gastroesophageal Reflux Not Completely Responsive to Proton Pump Inhibitors

Inclusion Criteria: * Patient is between 18 and 65 years of age at the Screening Visit; females must not be pregnant or must not be breastfeeding; * Patient has a confirmed diagnosis of gastroesophageal reflux disease, must be currently taking a proton pump inhibitor (PPI), and must be experiencing GERD symptoms as specified by the protocol. Exclusion Criteria: * Patient may not meet any of the excluded conditions specified in the protocol; * Patient is experiencing alarm symptoms such as GI bleeding, anemia, vomiting, dysphagia, or unexpected weight loss; * Patient has a clinically significant hypersensitivity or allergies to any of the active ingredients or excipients in the study medication.