Aim : Investigated the effects of Korean red ginseng supplementation on metabolic parameters such as cholesterol, blood pressure and glucose. Randomized Control Trial.
Methods : A randomized, double-blind, placebo-controlled, single-center study in 60 subjects who are not taking drugs that could affect metabolic and vascular function. Subjects will be randomized into a Korean red ginseng (3.0g/d) group or placebo group for a 4-week study. We will collect anthropometric measurements, blood for laboratory testing, inflammatory marker, hormones and mitochondrial DNA copy number. Subject : Older than 40 years of age, presented with metabolic syndrome. Subjects were excluded if they were taking drugs that could affect metabolic and vascular function, including BP control drug, anti-diabetic drugs and lipid-lowering drugs. Measurement : We will collect anthropometric measurements and blood for laboratory testing at the initial(week 0) and final (week 4)visits. Serum levels of blood glucose, insulin, total cholesterol, HDL-cholesterol,triglyceride, and DNA copy number of mitochondria.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
60
3.0 g/ d for 28 days
3g/day, 28days
Bundang CHA Hospital
Seoul, Kyeonggi-do, South Korea
Change from baseline in metabolic syndrome profile at week 4
Total cholesterol, HDL-Cholesterol, Glucose, Blood Pressure, Body weight
Time frame: Baseline and 4 weeks from intake of Ginsenoside
Change from baseline in hormones at week 4.
insulin ,cortisol, testosterone, somatomedin-c and DHEAS
Time frame: Initial and 4 weeks later
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