Peak Cough Flow and Cough Clearance in Patients With Muscular Dystrophy

N/ACompletedNCT02034305

University of Pittsburgh7 enrolled

Overview

This study is to determine whether physiologic measures (peak cough flow, measures of respiratory muscle strength including MIP, MEP ,SNIP, and spirometry) can predict spontaneous cough clearance (as measured by a nuclear medicine study) in children with neuromuscular disease. It will also determine whether airway clearance is augmented by high frequency chest wall oscillation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Duchenne Muscular Dystrophy

Eligibility

Sex: MALEMin age: 6 YearsMax age: 21 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 6-21; able to cooperate with study procedures * Duchenne Muscular Dystrophy OR Becker Muscular Dystrophy Exclusion Criteria: * Need for mechanical ventilation during the day * Recent (within 2 weeks) lower respiratory tract infection

Locations (1)

Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania, United States

Outcomes

Primary Outcomes

Spontaneous cough clearance

Time frame: Assessed at multiple time points over 30 minutes

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.