High Resolution Magnetic Resonance Imaging in Patients With Brain Tumors

Inclusion Criteria: * Male or female, age 18 years or older * Patient must meet at least one of the four following criteria regarding brain tumor diagnosis: * Histological diagnosis of a brain tumor * Histological diagnosis of systemic cancer and brain MR imaging suggestive of metastatic disease to the brain * Pre-operative brain MR imaging suggestive of a brain tumor * Radiographic diagnosis of brain tumor in an inoperable location (e.g., brainstem) * Patient able and willing to provide informed consent * Karnofsky Performance status \> 70% * Life expectancy greater than 3 months * Negative serum or urine pregnancy test or child bearing potential terminated by surgery, radiation, menopause or current use of two approved methods of birth control * Patients who are excluded from 7T MR imaging because of titanium implants that are not yet established to be safe at 7T remain eligible for the imaging at 3T \* Spanish speaking participants will be enrolled for this study Exclusion Criteria: * Body weight \>137 Kg (300 lbs) * Patient unable to provide informed consent * Karnofsky Performance status \< 70% * Patients who are claustrophobic or have other contraindications to MRI, such as implanted pacemaker device vascular clips, surgical clips, prosthetic valves, pacemakers, otologic implants * NYHA class III and IV congestive heart failure * Psychiatric or addictive disorders that preclude obtaining informed consent * Unstable angina * Sexually active patients of childbearing potential not using a reliable contraceptive method * Pregnant or lactating women * Women of childbearing potential who refuse a pregnancy test (performed during screening)