Quantitative information on the biomechanical properties of the ecto-cervix in mid-pregnancy will be compared between women with term vs. preterm delivery. We aim to demonstrate that biomechanical data (ASP and CCI) might complement morphological data (CL) to improve prediction of preterm delivery. It is expected that women with preterm delivery will show stronger weakening of cervical tissue. Aspiration (ASP) and cervical CCI (cervical consistency index) measurements are performed at mid-pregnancy: detection at this time point is useful for therapy and biomechanical modifications are already significant so to enable differentiation by biomechanical measurements (ASP and CCI).
Study Type
OBSERVATIONAL
Enrollment
1,002
No intervention is done except for measuring the stiffness of the cervix in pregnant women
University Hospital of Leuven
Leuven, Belgium
Kantonsspital Aarau, Frauenklinik
Aarau, Switzerland
Kantonsspital Baden, Frauenklinik
Baden, Switzerland
Difference in cervical stiffness in women with/without preterm delivery
The biomechanical measurements and morphological data obtained at mid-pregnancy are compared between women with/without preterm delivery and are expected to significantly differ. The diagnostic power for preterm delivery of aspiration, CCI and the other factors will be determined.
Time frame: Measurements between 18+0/7 and 22+0/7 weeks of pregnancy and postpartum
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Universitätsspital Basel, Frauenklinik
Basel, Switzerland
Kantonsspital Frauenfeld, Frauenklinik
Frauenfeld, Switzerland
Hôpitaux universitaires de Genève (HUG)
Geneva, Switzerland
Kantonsspital Luzern, Frauenklinik
Lucerne, Switzerland
Kantonsspital Münsterlingen
Münsterlingen, Switzerland
Kantonsspital St. Gallen, Klinik für Gynäkologie und Geburtshilfe
Sankt Gallen, Switzerland
Kantonsspital Winterthur
Winterthur, Switzerland
...and 3 more locations