Korean Red Ginseng in Treating Patients With Fatigue Caused by Chemotherapy for Colorectal Cancer

Inclusion Criteria: * 20 years and older * Person who agreed to participate in this study and signed voluntarily on the written informed consent form * Person who is confirmed as colorectal cancer through histological and image diagnosis and scheduled for adjuvant or palliative therapy with mFOLFOX-6 regimen * Fertile patients with negative pregnancy test confirmed and who has agreed to use effective contraception * Person who is able to fully communicate with the physician about his/her fatigue status and is able to completely fill out the questionnaires * Life expectancy more than 6 months * Performance status of ECOG grade 0\~1 * Hb ≥ 9g/dL * Person with moderate liver function (AST, ALT ≤ 2.5 × ULN) * Person with moderate renal function (Cr ≤ 1.5 × ULN) Exclusion Criteria: * Pregnant or nursing women * Primary brain cancer, brain metastases or other CNS malignancy, including CNS lymphoma * No controlled pain despite the use if analgesics. * Person showing hypothyroidism despite the hormone treatment * Person with insomnia despite an appropriate treatment * No controlled hypertension (DBP \>100mmHg or SBP \>160mmHg) * Person who has experience of hypersensitivity to the trial drug (ginseng) components * Person with autoimmune disorders (Multiple sclerosis, Lupus, rheumarthritis etc.) * Person who is alcoholic dependent or has psychiatric disorder * Person who has cognitive or psychiatric problems * Person who has an experience of chemotherapy agents use 6 months before a screening visit * Person who had a surgery 2 weeks before a screening visit * Person who had taken herbal medicinal product (including Chinese medicine) 4 weeks before the screening visit * Person who has medical status that is judged to affect the result or who is judged as inappropriate for the study by the physician