Sleep Disordered Breathing in Children: Inflammation and Oxidative Stress

N/AUnknownNCT02040701

Tel-Aviv Sourasky Medical Center300 enrolled

Overview

The purpose of the study is to measure markers of inflammatory and oxidative stress known to be associated with cardiovascular morbidity in snoring children. In addition, to measure markers of local inflammation and to evaluate the response to treatment.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Sleep Disordered Breathing (SDB)Endothelial Dysfunction

Eligibility

Sex: ALLMin age: 6 MonthsMax age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * children ages 6 months-18 years * suspected sleep-disordered breathing or will attend the pre-operative ENT clinic for adenoidectomy or adenotonsillectomy Exclusion Criteria: * craniofacial abnormalities * neurological disorders * genetic disorders * infectious disease * chronic inflammatory disease * any underlying chronic medical condition

Locations (1)

Dana Children's hospital, Tel Aviv Medical Center

Tel Aviv, Israel

RECRUITING

Outcomes

Primary Outcomes

Plasma inflammatory-markers

Sleep disordered breathing (SDB) in children is associated with increased markers of inflammation, atherogenesis and oxidative stress.

Time frame: After the blood analyzed

Central Contacts

Riva Tauman, Dr.

CONTACT

tauman@tlvmc.gov.il

Data from ClinicalTrials.gov

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