Paradigm Shift in the Treatment of Patients With ACS

Inclusion Criteria: * Men or non-pregnant women \>18 years of age and \< 75 years of age * Patients undergo cardiac catheterization for ACS. Patients with STEMI, NSTEMI, and UAP will be included. STEMI will be defined as continuous chest pain for \>30 minutes, arrival at the hospital within 12 hours from chest pain onset, ST-segment elevation \>0.1 mV in at least two contiguous leads, or new left bundle-branch block on the 12-lead electrocardiogram (ECG), and elevated cardiac markers (troponin T/I or creatine kinase-MB). NSTEMI will be defined as a progressive crescendo pattern of angina or angina at rest, in the absence of ST-segment elevation on the 12-lead ECG, with elevated cardiac markers. UAP will be defined as new onset angina, progressive crescendo pattern of angina, or angina at rest. * Culprit lesion located in a native coronary artery * TIMI flow grade 3 and diameter stenosis \< 70% on angiogram * Definite erosion defined by OCT * Patients able to provide written informed consent Exclusion Criteria: Left ventricular ejection fraction \< 30%. * Life expectancy \< 1 year. * Contraindication to the contrast media. * Creatinine level \> 2.0 mg/dL or end-stage kidney disease. * Serious liver dysfunction. * Patients with hemodynamic or electrical instability (including shock). * Any contraindication against the use of ticagrelor. * Investigator considers the patient is not suitable.