Pulmonary Rehabilitation in Patients With Sarcoidosis

N/ACompletedNCT02044939

University Hospital, Lille38 enrolled

Overview

The primary objective of the study is to assess the improvement of daily activity in subjects with Stage IV Pulmonary Sarcoidosis one year after the conduct of a pulmonary rehabilitation program. The secondary objectives are the following: * assess the improvement of daily activity at several times : 2, 6 and 12 months after the beginning of a pulmonary rehabilitation program * assess the improvement of exercise capacity by tests used in medical practice * assess the correlation between daily activity and exercise capacity * assess the improvement of dyspnea * assess the improvement of quality of life and psychological state

The primary objective of the study is to assess the improvement of daily activity in subjects with Stage IV Pulmonary Sarcoidosis one year after the conduct of a pulmonary rehabilitation program The secondary objectives are the following : * assess the improvement of daily activity at several times : 2, 6 and 12 months after the beginning of a pulmonary rehabilitation program * assess the improvement of exercise capacity by tests used in medical practice * assess the correlation between daily activity and exercise capacity * assess the improvement of dyspnea * assess the improvement of quality of life and psychological state

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Stage 4 Pulmonary Sarcoidosis

Interventions

Pulmonary rehabilitation programOTHER

Pulmonary rehabilitation program should follow ATS/ERS Guidelines (2006)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Stage IV Sarcoidosis * No hospitalization for respiratory distress in the 3 months preceding the inclusion * Dyspnea on exertion * Age over 18 years Exclusion Criteria: * Physical disability does not allow the creation of a rehabilitation program * Inability to give written consent to the study * Refusal of contraception in women of childbearing age * Inability to participate in the entire study * No cover by the social security system * Inability to perform self-questionnaires etude The trial does not include special populations include: * Pregnant women * Breastfeeding women * People in emergencies * Persons unable to consent * Persons deprived of liberty

Locations (11)

Clinique des Maladies Respiratoires, CHRU de LILLE

Lille, Nord, France

Service de Pneumologie, CH Béthune

Béthune, Pas De Calais, France

Service de Pneumologie, CH Arras

Arras, France

Outcomes

Primary Outcomes

Daily activity assessed by time (in minutes) spent in moderate activity (superior to 2,5 MET)

In everyday life, it corresponds to a walking in 5 km/h or in domestic chores. This measure will be realized by using Armband's accelerometer, in ambulatory. The measure will be realized over a period of 4 full days including the weekend.

Time frame: 12 months

Secondary Outcomes

Daily activity assessed by time spent in moderate activity (superior to 2,5 MET)

Time frame: 2 and 6 months

exercise capacity assessed by symptom-limited cardiopulmonary exercise test, 6 minutes walk test, endurance test on bicycle, St Etienne questionnaire, 6 minutes stepper test