In this study, we aim to investigate the incidence of the adverse reactions, the effectiveness and the gene polymorphism associated with the plasma level of sulfamethoxazole-trimethoprim and their metabolites (including N4-acetyl-sulfamethoxazole, sulfamethoxazole hydroxylamine and sulfamethoxazole-nitroso). And we also aim to investigate the factors associated with the sulfamethoxazole-trimethoprim induced acute psychosis.
Study Type
OBSERVATIONAL
Enrollment
1,000
National Taiwan University Hospital
Taipei, TW, Taiwan
ACTIVE_NOT_RECRUITINGNational Taiwan University Hospital
Taipei, TW, Taiwan
RECRUITINGHigh performance liquid chromatography for drug plasma concentration
The plasma concentration will not be measured until the patient's treatment course completed.
Time frame: Participants will be followed for the duration of the treatment course, an expected average of 21 days
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