The purpose of this study is to analyze the safety and feasibility of the implantation of autologous mesenchymal stem cells (MSCs) expanded "in vitro" and administered directly in the lung line of suture as a treatment for patients at risk of postoperative air leaks after lung resection.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
10
Patients at risk of prolonged postoperative air leak will be treated by local administration of autologous mesenchymal cells expanded in vitro
University Clinical Hospital of Salamanca
Salamanca, Salamanca/Castilla León, Spain
RECRUITINGSafety of the procedure
Security is measured in terms of: Adverse effects derived from the implantation of the CSM
Time frame: During the procedure and postoperative period (48 hours)
Analyze the efficacy of the procedure
Clinical: * Duration of postoperative air leak * Amount of leakage and trends measured by digital memory device * Cardiorespiratory complications Radiological: * Pneumothorax on chest radiograph.
Time frame: Postoperative period (48 hours), 1 month, 3 months, 6, 12 and 24 months
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