The aim of this study is to evaluate calcium ionophore solution on fertilization rate of patients during intracytoplasmic sperm injection who have poor ovarian reserve
During ICSI cycle , female patients who have poor ovarian reserve have low oocyte numbers. So by calcium ionophore solution which we know that it can increase fertilization rate in males who have azospermia or globozoospermia. we planned to check if this solution can increase fertilization rate also in poor ovarian reserve patients?
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
NONE
Enrollment
162
After microinjection of sperm into the oocyte, oocytes are incubated for 15 minutes in a 30 microlitre droplet of calcium ionomycin solution
baskent university obstetric and gynecology, reproductive endocrinology and IVF unit
Adana, Kisla, Turkey (Türkiye)
RECRUITINGcalcium ionophore solution effect on fertilization rate
Before Intracytoplasmic sperm injection adding calcium ionophore solution to the medium can increase fertilization rate of oocytes or not?
Time frame: 18 hours
Calcium ionophore solution increase on going pregnancy rate
İf the calcium ionophore can increase fertilization rate , pregnancy rate up to 20 weeks, can increase or not?
Time frame: up to 21 weeks
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