This is an open multicentre, randomized study to compare two treatment arms. One arm called "intensification of multiple injections" in which the patient will receive one supplementary injection of LEVEMIR®: that is to say 5 injections per day, and an arm called "continuous insulin infusion" via an external pump with APIDRA®. In the pump arm: a favorable effect in terms of improved insulin sensitivity, improved metabolic equilibrium, a decrease in the area under the baseline and prandial hyperglycemia curve noted during the continuous glycemia recording; an improvement in quality of life compared with treatment using multiple injections.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
14
CHU de Besancon
Besançon, France
CHU de Dijon
Dijon, France
Mixed measurement of insulin secretion and insulin resistance
Time frame: Change from baseline insulin secretion and insuline resistance at 6 month after starting the treatment
Decrease in the time spent in baseline and prandial hyperglycemia
Time frame: During the 6 months following initiation of the treatment
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