Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples

N/ACompletedNCT02051101

University of California, Irvine19 enrolled

Overview

The purpose of this study is to investigate the pathogenic mechanisms of Port Wine Stain, collect biopsy samples and blood samples to characterize exosomes and metabolites from Port Wine Stain.

The researcher can detect the defects in nervous system innervation to cutaneous blood vessels contribute to the pathogenesis of Port Wine Stain . Unveiling the pathogenic mechanisms of PWS is crucial to the design of new therapeutic strategies and can use the results to improve current PWS therapeutic outcomes.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Port-Wine Stain

Interventions

Biopsy sample from Port Wine Stain BirthmarkOTHER

Biopsy sample from Port Wine Stain Birthmark

Eligibility

Sex: ALLMin age: 1 DayHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Male or female of all ages. * Not pregnant. * Has diagnosis of port wine stain on the arms, legs, chest, bac. * Ability to understand and carry out subject instructions. * Subject willing to have skin biopsies on port wine stain and normal skin areas. Exclusion Criteria: * Pregnant women. * Port Wine Stain on the face. * History of skin cancer. * Current participation in an investigational drug evaluation * Concurrent use of known photosensitizing drugs.

Locations (1)

Beckman Laser Institute

Irvine, California, United States

Outcomes

Primary Outcomes

Characterization of Port Wine Stain Birthmark tissue sample

Time frame: up to 4 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.