The purpose of this study is observe clinical practice including glucocorticoids treatment in AECOPD in China.
It is widely recognized that the global social and economic burden of Chronic obstructive pulmonary disease (COPD) is high; affecting an estimated 64 million people worldwide. It was reported the prevalence of COPD in China population over 40 years old is about 8.2% (Zhong Nanshan et al, 2007). According to the report on China Chronic Disease, COPD is the second disease of Disability Adjusted Life Years. The economic burden of COPD is tremendous in China. Cost analysis in 2006 showed that every COPD patient in urban would pay 1732.24 $ on medical cost every year, indirect cost on nurse and traffic is 231.6 $, total cost would account for 40% of average family income in 2006(Chiang CH.,2008).AECOPD is one of most important cause leading to COPD death. Corticosteroid is essential for AECOPD management and recommended by domestic and international guidelines. But it shows that corticosteroid use for treating AECOPD in China is around 70% from market research in big hospitals, and less report about how steroid is used for AECOPD management was published, including distribution, dosage, treatment duration, etc. The healthcare resources utilization for treating AECOPD in China is also unclear.
Study Type
OBSERVATIONAL
Enrollment
5,095
Research Site
Hefei, Anhui, China
Research Site
Beijing, Beijing Municipality, China
Research Site
Langfang, Hebei, China
Research Site
Percentage of glucocorticoids treatment for AECOPD
Time frame: day 1 to up to 30 days (Hospital discharge)
Percentage of oral /intravenous/ inhaled steroid therapy in patients treated with glucocorticoids, mean dosage, regimen and treatment duration via different administration route in hospital
Time frame: day 1 to up to 30 days (Hospital discharge)
Percentage of antibiotics treatment for AECOPD by clinicians during the hospitalization.
Time frame: day 1 to up to 30 days (Hospital discharge)
Mortality caused by AECOPD and recorded as primary cause of death by clinicians
Time frame: day 1 to up to 30 days (Hospital discharge)
Percentage of antibiotics treatment via different administration route for AECOPD, mean treatment duration via different administration route in hospital
Time frame: day 1 to up to 30 days (Hospital discharge)
Endotracheal intubation rate in treatment of AECOPD
Time frame: day 1 to up to 30 days (Hospital discharge)
Pneumonia rate at the diagnose of AECOPD and in treatment of AECOPD
Time frame: day 1 to up to 30 days (Hospital discharge)
Hospitalization duration and treatment cost due to AECOPD as primary cause
Time frame: day 1 to up to 30 days (Hospital discharge)
Percentage of treatment category before AECOPD and at discharge
Time frame: day 1 to up to 30 days (Hospital discharge)
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Baotou, Inner Mongolia, China
Research Site
Hohhot, Inner Mongolia, China
Research Site
Yinchuan, Ningxia, China
Research Site
Shanghai, Shanghai Municipality, China
Research Site
Taiyuan, Shanxi, China
Research Site
Xi’an, Shanxi, China
Research Site
Beijing, China
...and 3 more locations
Clinical efficacy and safety within different administration route of corticosteroid treatment
Time frame: day 1 to up to 30 days (Hospital discharge)