Purpose of this randomized controlled trial is to test the efficacy of the individual psychotherapeutic intervention Managing Cancer and Living Meaningfully (CALM) in a German sample of patients with advanced cancer. The interventions aim is to reduce depression and distress and support psychological well-being.
Principal hypothesis: The manualized psychotherapeutic intervention (CALM) will result in a significantly greater reduction in depression and psychological distress compared to a non-manualized supportive psycho-oncological intervention. Secondary hypothesis: The manualized psychotherapeutic intervention (CALM) will further result in a significantly improve psychological well-being, quality of life and sense of meaning compared to a non-manualized supportive psycho-oncological intervention.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
206
Managing Cancer and Living Meaning Cancer (CALM) is a short-term individual psychotherapy for patients with advanced disease.
Supportive psycho-oncological intervention.
Department of Medical Psychology and Medical Sociology, University Medical Center Leipzig
Leipzig, Saxony, Germany
Department of Medical Psychology, University Medical Center Hamburg-Eppendorf
Hamburg, Germany
Depression module of the Patient Health Questionnaire (PHQ-9)
A reliable and valid 9-item measure of depression.
Time frame: 6-months
Beck Depression-Inventory II (BDI-II)
A reliable and valid 21-item self-report instrument for evaluating the severity of depression.
Time frame: 6-months
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