Drug-Drug Interaction Study Between CJ-12420 and Clarithromycin in Healthy Male Subjects

Inclusion Criteria: * Healthy male volunteers in the age between 19 and 45 years old * Body mass index(BMI) in the range of 19 to 28 kg/m2 * Understand the requirement of the study and voluntarily consent to paticipate in the study Exclusion Criteria: * History of clinically significant medical history or disease (hepatic, kidney, gastrointestinal,respiratory, musculoskeletal, endocrine,neuro-psychiatric, haemato-oncologic,urinary tract, cardiac arrhythmia and cardiovascular system) judged by investigator. * Clinically significant abnormal laboratory results within at least 28 days prior to the first day of drug administration. AST or ALT \> 1.25 times of upper limit value Total bilirubin \> 1.5 times of upper limit value estimated GFR :less than 80 mL/min * Clinically significant abnormal ECG results within at least 28 days prior to the first day of drug administration PR ≥ 210 msec QRS ≥ 120 msec QT ≥ 500 msec QTcF ≥ 500 msec * Clinically significant hypersensitivity reaction against investigational drug or other drugs * history of drug abuse or "positive" results from drug screening test. * Take medicine such as prescription medicine or herbal medicine, over-the-counter drug, vitamin supplements * Person who have intake history of food or drug which can affect drug absorption, drug distribution, drug metabolism, and drug excretion and bowel activity * Volunteer have a history of donation of whole blood donation, apheresis, transfusion * Volunteer a heavy drinker(30g/day), smoker(10 cigarettes/day), heavy caffeine consumer(400mg/day)