The purpose of this study is to examine whether 4 weeks daily intake of krill oil can change the omega-3 index (content of the long chained fatty acids EPA and DHA in relation to the total fatty acids) in the membrane in red blood cells. We investigate this at two different doses. Furthermore, the purpose of the study is also to examine the effect of the krill oil intake on plasma lipids (triacylglycerol, phospholipids and cholesterol), plasma fatty acid composition, as well as product tolerance in healthy, young individuals.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
35
3 capsules krill oil per day
9 capsules krill oil per day
Department of Clinical Science, University of Bergen
Bergen, Bergen, Norway
Fatty acid composition in red blood cells (the membrane)
Change in fatty acid composition and omega-3 index (sum of % EPA and DHA)
Time frame: Day 0 (baseline), and day 28 (end)
Fasting plasma lipid status
* Change in triacylglycerol levels. * Change in phospholipid levels. * Change in cholesterol levels (total, ester, free, HDL, LDL).
Time frame: Day o (baseline), and day 28 (end)
Fatty acid composition in plasma.
Change in fatty acid composition and omega-3 index (sum of % EPA and DHA).
Time frame: Day 0 (baseline), and day 28 (end)
Fasting glucose and glucose tolerance.
Change in fasting glucose and glucose tolerance.
Time frame: Day 0 (baseline), and day 28 (end)
Tolerance of and compliance with intervention
Questionnaire-based
Time frame: Day 28 (end)
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