Immediate Implant Breast Reconstruction

Inclusion Criteria: * Histologically confirmed breast carcinoma * Patients planned for mastectomy with immediate single stage breast reconstruction using an acellular dermal matrix (Strattice™, LifeCell Corporation) * Patients planned to receive postoperative chest wall irradiation * Age ≥ 18 years old * WHO performance status 0-1 * Affiliation to a social security system * Informed consent signed prior any study specific procedures Exclusion Criteria: * Inflammatory breast cancer * Tumors with extensive involvement of the skin * Use of tissue expander * Indication of postoperative chemotherapy * Patients planned for bilateral mastectomy * History of previously treated ipsilateral breast carcinoma * Usual contraindications for ADM * Medical debility precluding surgical treatment * Psychological, social, geographical disorders or any other condition that would preclude study compliance (treatment modalities and study follow-up). * Pregnancy or breast feeding * Inability to attend or comply with interventions or follow-up scheduling, disability or difficulty preventing a proper understanding of trial instructions * Legal inability or restricted legal ability