Selection Criteria for Safe Hepatectomy for Hepatocellular Carcinoma

N/ACompletedNCT02056041

University of Milan336 enrolled

Overview

Selection criteria for safe hepatectomy for HCC are not well established. The aim of this study was the validation of the selection criteria for safe hepatectomy for hepatocellular carcinoma.

All consecutive patients submitted to hepatectomy for HCC based on the same preoperative selection criteria from our prospectively-maintained liver unit database. Such criteria included the value of bilirubin (BIL), the value of cholinesterases (CHE), the presence of ascites, the presence of esophageal varices, and the rate of residual liver volume.

Study Type

OBSERVATIONAL

Enrollment

336

Conditions

Hepatectomy Hepatecellular Carcinoma Cirrhosis

Interventions

HepatectomyPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * any patient with HCC submitted to hepatic resection at our Unit in the established frame time Exclusion Criteria: * any patient with missing data or lost at follow-up

Locations (1)

Humanitas Research Hospital

Rozzano, Milan, Italy

Outcomes

Primary Outcomes

Safety of surgery for HCC

The primary endpoint was the validation of our selection criteria for safe hepatectomy for HCC in regards to postoperative complications. The role of total bilirubin and cholinesterases was analzyed together with other clinical parameters.

Time frame: 90 days

Secondary Outcomes

Score systems HCC

The secondary endpoint was the testing of the most common score systems for HCC, which are the CPT score, the MELD score, and the APRI score.

Time frame: 90 days

Data from ClinicalTrials.gov

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