This study is to evaluate the safety/tolerability and pharmacokinetics of the combinations of gemigliptin 50mg and metformin HCl extended release 1000mg in comparison to each component administered in healthy male volunteers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
NONE
Enrollment
24
Coadministration of gemigliptin 50mg and metformin HCl extended release 1000mg, for 1 day
Administration of combination of gemigliptin 50mg/metformin HCl sustained release 1000mg, for 1day.
Asan Medical Center
Seoul, South Korea
AUClast
To evaluate AUClast of gemigliptin and metformin
Time frame: up to 48h post-dose
Cmax
To evaluate Cmax of gemigliptin and metformin
Time frame: up to 48h post-dose
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