A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis

Inclusion Criteria: * Male or Female subjects from 18 to 45 years of age in good general health. * Primary axillary hyperhidrosis of at least 6 months duration. * Hyperhidrosis Disease Severity Score (HDSS) of 3 or 4 at baseline. * Gravimetric test at baseline indicating at least 100mg of axillary sweat production in a 5 min period. * Use of a medically appropriate contraceptive method. Exclusion Criteria: * Prior axillary use of botulinum toxin within 2 years of study entry. * Prior iontophoresis treatment for axillary hyperhidrosis within 12 weeks of study entry. * Prior surgical procedures for hyperhidrosis or surgical procedures in the axillary areas for any reason. * Use of anticholinergic treatment, beta-blocker, alpha-adrenergic or other prescription treatment for hyperhidrosis. * History of diabetes mellitus, thyroid disease, malignancy, glaucoma, intestinal obstructive or motility disease, obstructive uropathy, myasthenia gravis, prostate hypertrophy, neurological conditions or cardiac abnormalities. * Known condition that may cause hyperhidrosis. * Use of an investigational drug within 30 days prior to entry into this study.