Phase ⅡStudy of Pinocembrin Injection to Treat Ischemic Stroke

Inclusion Criteria: * 35-75 hospitalized patients * Patients with acute stroke ≤24h * NIHSS score 6-20 at time of enrollment , the score ≥2 of item 5 and/or 6 * For the first time or always without obvious sequelae of stroke disease(mRS≤1） * Informed consent Exclusion Criteria: * The disease such as Acute intracerebral hemorrhage,tumor and encephalitis which cause similar symptoms * Patient with NIHSS level of consciousness score≥2 or dementia,or other patients who the investigator think that don't fit into the study * TIA * Symptoms of disease rapidly improving during the randomized * Severe hypertension(SBP \> 200 mmHg or DBP \>110 mmHg) * Inadequate liver function(AST or ALT greater than 2 times the upper limit of normal values);Renal impairment (Creatinine clearance \<60ml/min） * Severe system or viscera organic disease * Have used other neuroprotectant or other experimental drugs * Patient who are unlikely to complete the study that due to a severe clinical condition * Pregnant or breast-feeding * Participation in a previous clinical study within 30 days * Meets all other exclusion criteria