Photoaging is caused by the superposition of chronic ultraviolet (UV)-induced damage on the intrinsic aging process, and accounts for the majority of age-associated changes in skin appearance. Reactive oxygen species (ROS) likely contribute to this process. Strategies utilizing endogenous skin antioxidants as well as plant-derived or synthetic compounds have been examined. Cocoa beans fresh from the tree are exceptionally rich in polyphenols, such as flavanol, and have a higher antioxidant capacity. The present study is designed to investigate the effects of long-term intake of a product rich in cocoa flavanols on facial wrinkles, hydration, elasticity and photosensitivity.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
64
Seoul National University Hospital
Seoul, South Korea
Change from baseline in skin wrinkles at week 24
Facial wrinkles in the crow's feet area measured as R1-3
Time frame: baseline, week 24
Change from baseline in skin elasticity at week 24
Facial elasticity measured as R2, R5, R7
Time frame: baseline, week 24
Change from baseline in minimal erythema dose at week 24
Time frame: baseline, week 24
Change from baseline in skin hydration at week 12
Skin hydration measured by Corneometer
Time frame: baseline, week 12
Change from baseline in skin color at week 12
Skin color measured as erythema index and melanin index
Time frame: baseline, week 12
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