The addition of an anti-inflammatory agent could be a valid option for controlling choroidal neovascularization, as simply inhibiting VEGF addresses neither the multifactorial pathogenesis of choroidal neovascularization nor the underlying cause of VEGF production.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
3 monthly ranibizumab, then as needed Ketorolac TID
3 monthly ranibizumab, then as needed
Spedali Civili di Brescia
Brescia, BS, Italy
mean change in study eye visual acuity as measured by the best-corrected ETDRS letter score
Time frame: 12 months
mean change in central macular thickness
Time frame: 12 months
mean number of intravitreal injections over the 12-month period
Time frame: 12 months
adverse ocular events at 12 months
Time frame: 12 months
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