The purpose of the study is to establish drug-induced liver injury databases in China, make criteria for Chinese drug-induced liver injury patients and evaluate the application of certain circulating miRNA in diagnosis or treatment of drug-induced liver injury.
Firstly, this study collects some retrospective data. Analyse these data and establish certain unique diagnostic criteria for Chinese. Then collect prospective data and validate the criteria. Otherwise,collect blood sample or other sample of the patients and study certain miRNA in diagnosis or treatment of drug-induced liver injury.
Study Type
OBSERVATIONAL
Enrollment
800
Beijing Ditan Hospital
Beijing, China
histological features of drug-induced liver injury obtained by liver biopsy
Liver biopsy is the main method
Time frame: within six months of the DILI onset date
clinical features of drug-induced liver injury assessed by serum parameters of liver function
serum parameters of liver function is the focus
Time frame: participants will be followed for the duration of hospital stay, an expected average of 3 weeks
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