Impact of COX2 on Sera Biomarkers From Obese Subjects

Inclusion Criteria: * At least 18 years of age * Post-menopausal as confirmed by medical history * Ability to understand the purposes and risks of the study and has signed a written informed consent form approved by the investigator's IRB/Ethics Committee Exclusion Criteria: * Evidence of active cancer (patients with a prior history of malignancy are encouraged to participate, but due to cytokine levels associated with malignancy there must be no evidence of disease) * Cachexia * Active systemic illness (infection including viral illnesses such as Hepatitis and HIV) * Chronic use of aspirin of omega-3 free fatty acid supplementation within the last 60 days (defined as greater than or equal to 7 consecutive days) * Known hypersensitivity to aspirin and/or omega-3 fatty acids * Actively receiving a physician-directed regimen of aspirin and/or receiving herapeutic/prophylactic anticoagulation * Any aspirin or omega-3 free fatty acid supplementation within the last 14 days * Subjects who are pregnant * History of medical noncompliance