Gait, Stair Climbing and Postural Stability in Knee Osteoarthritis Patients After Hyaluronic Acid Injection

Phase 3CompletedNCT02063373

University of Malaya85 enrolled

Overview

Treatment: five intro-articular Hyaluronic Acid injection Assessment has two parts, that are as follow: 1. Postural stability and risk of fall assessment using Biodex stability index and "Timed up and Go" test 2. Gait and stair climbing assessment using Vicon motion capture system synchronized with four force plates. For knee OA subjects, assessment was done in week one or before injection; and for healthy controls one assessment was performed.

This study aimed to assess the effect of hyaluronic acid injection on Postural stability, biomechanics of gait and stair climbing in individuals with bilateral knee osteoarthritis (OA). Participants were individuals with knee OA (control and treatment) and healthy people.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Bilateral Knee Osteoarthritis

Interventions

Hyaluronic acidOTHER

treatment: Weekly intra-articular hyaluronic acid injection (20 MG / 2ML) into both knees for five weeks.

Eligibility

Sex: ALLMin age: 50 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Mild and moderate bilateral knee osteoarthritis * Age between 50 and 70 years Exclusion Criteria: * Recent Lower limb injury * Diabetic * Knee or hip replacement * Knees HA injection in last 6 months * Any neuromuscular disease such as stroke and Parkinson