Postoperative Analgesic Effects of Dexmedetomidine for Transversus Abdominis Plane Block

Phase 4CompletedNCT02064530

TC Erciyes University90 enrolled

Overview

the aim of this study is evaluate postoperative analgesic effects of dexmedetomidine added to bupivacaine on TAP block in patients undergoing lower abdominal surgery.

TAP block is being used a method of multimodal balanced analgesia reduces postoperative pain, opioid requirement after surgery and adverse effect of opioid such as sedation, nausea vomiting and ileus. Dexmedetomidine ,an alfa-2 adrenoreceptor agonist, is being used and adjuvant capable of prolonging duration of sensory and motor block on nerve blocks.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Pain

Interventions

BupivacaineDRUG

21 ml 0.5 %bupivacaine is applied interfasially

DexmedetomidineDRUG

1 ml dexmedetomidin + 20 ml 0.5 % bupivacaine are applied interfasially

serum physiologicDRUG

21 ml serum physiologic is applied interfasially

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA 1-2 * 18-65 aged * patient undergoing lower abdominal surgery Exclusion Criteria: * chronic opioid consumption * bupivacaine and dexmedetomidine allergies * coagulopathy * infection at the needle insertion side * chronic liver and kidney disease

Locations (1)

Erciyes universty

Kayseri, Melikgazi, Turkey (Türkiye)

Outcomes

Primary Outcomes

opioid consumption

patient controlled analgesia

Time frame: postoperative 1 day

Secondary Outcomes

visual analog scale

Time frame: postoperative 1 day

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.