The aim of this open, controlled, multicentre biomedical research study is to identify new markers specifically associated with Horton's disease. This would make it possible to improve the diagnosis and management of this disease. Participation consists in taking one or several blood samples depending on the group patients/controls.
Study Type
OBSERVATIONAL
Enrollment
143
CHU de BESANCON
Besançon, France
CHU de DIJON
Dijon, France
CH de METZ
Metz, France
Quantification of specific cytokines of the Th17 immune response (IL-17 A and IL-23) in the serum
Time frame: Up to 6 months
Quantification of LTh17 by flow cytometry
Time frame: Up to 6 months
Measurement of the activation level of genes specifically involved in Th17 response using RT-PCR on frozen mRNA
Time frame: Up to 6 months
Measure the ability of Treg to proliferate and to synthesize IL-17 in response to different antigenic stimulations
Time frame: Up to 6 months
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