Urine Sample Collection From FOP Patients

Inclusion Criteria: * Male and female patients ≥ 5 and ≤ 35 years of age with a diagnosis of FOP. * Physically able to provide first-morning urine sample of at least 30 mL * Able to communicate well with the investigator, to understand and comply with the requirements of the study * About half of the patients enrolled should have a flare-up, which is defined as an acute exacerbation of disease activity characterized by two or more of the following symptoms: pain, swelling, decreased range of motion, impaired function Exclusion Criteria: * Diagnosis of diabetes * Diagnosis of other systemic inflammatory disorder (juvenile idiopathic arthritis, systemic lupus erythematosus, etc.) * Diagnosis of cancer other than nonmelanomatous skin cancer.