To evaluate the efficacy of locally delivered ozone gel as an adjunct to conventional periodontal therapy on selected clinical parameters as well as alveolar bone density (BD) and superoxide dismutase (SOD) activity in patient with chronic periodontitis.
In this study, the investigators tested the effect of ozone gel as a local delivery system in treatment of chronic periodontitis in term of probing pocket depth reduction, mean gain in clinical attachment level, a more rise in BD values as well as greater reduction in SOD activity compared to scaling and root planing (SRP) alone.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
40
October 6 University
Cairo, Egypt
Superoxide dismutase activity
Superoxide dismutase activity in the gingival crevicular fluid was carried out at baseline, 1, 3 and 6 months post treatment.
Time frame: 6 months
Plaque Index
plaque index was recorded at baseline and at 1, 3 and 6 months post treatment.
Time frame: 6 months
Gingival index
Gingival index was recorded at base line,1,3,6 months post treatment
Time frame: 6 months
Probing pocket depth
Probing pocket depth was recorded at base line, 1, 3, 6 months post treatment
Time frame: 6 months
Clinical attachment level
Clinical attachment level was recorded at baseline, 1, 3 and 6 months post treatment
Time frame: 6 months
Bone density
Bone density was carried out using Digora software (Digora system, Soredex, Orion Corp., Finland) at baseline and 6 months
Time frame: 6 months
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