Both intravenous and oral acetaminophen have been shown to reduce post-operative pain scores when given preoperatively. This study investigates if there is a difference between the intravenous and the oral forms when given preoperatively to patients undergoing lumbar microdiscectomy. We hypothesize that the intravenous formulation does not improve pain scores or decrease opioid consumption during the first postoperative day compared to the oral formulation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
100
1000 milligrams given orally before surgery
1000 milligrams of intravenous acetaminophen given before surgery
Thomas Jefferson University Hopsital
Philadelphia, Pennsylvania, United States
RECRUITINGPostoperative pain scores
Pain scores are measured using a visual analog scale with patient at rest and also with movement of the lower extremities at four separate times following surgery.
Time frame: Day of surgery
Quantity of intraoperative and postoperative opioids administered.
All doses of opioids given on the day of surgery will be recorded.
Time frame: Day of surgery
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