Background: Although it is now possible to diagnose Borderline Personality Disorder (BPD) in adolescents younger than 18 years according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-V), and studies indicates that BPD can be reliably diagnosed in adolescence, only a few evidence based treatment programmes for adolescent BPD exists. Mentalization-based treatment (MBT), including group psychotherapy, has repeatedly shown to be effective in treating adult BPD, but in the case of adolescents, only individual MBT have been tested and found to be effective. Aims/hypotheses: We will test whether group based MBT (MBT-G), including an introductory programme for patients (MBT-I) and their parents (MBT-P) is more effective than Treatment As Usual (TAU) in treating adolescents with BPD or subthreshold BPD. Methods/Design: 112 patients referred to child and adolescent psychiatric clinics in Region Zealand will be randomized to either MBT or TAU. Inclusion criteria: Meeting DSM-V BPD-criteria at the threshold (five criteria) or sub threshold level (4 criteria). Follow-up will be at three and 12 months. Discussion: Early intervention is especially important in relation to personality psychopathology and has long-term benefits for patients, their families and society. In addition to being cost effective, using the group modality in the treatment of BPD may have several advantages. This is the first Randomized Controlled Trial (RCT) to test the effectiveness of MBT in groups for adolescents.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
112
Treatment As Usual
Child and Adolescent Psychiatric Department, Region Zealand
Roskilde, Region Sjælland, Denmark
The Borderline Personality Feature Scale for Children (BPFS-C)
Time frame: Change from Baseline in BPFS-C at 40 weeks
The Borderline Personality Feature Scale for Children (BPFS-C)
Time frame: Change from Baseline in BPFS-C at 10 weeks
The Borderline Personality Feature Scale for Children (BPFS-C)
Time frame: Change from baseline at 20 weeks
The Borderline Personality Feature Scale for Children (BPFS-C)
Time frame: Change from baseline at 30 weeks
Becks Depression Inventory for Youth
Time frame: Change from Baseline in at 10 weeks
Becks Depression Inventory for Youth
Time frame: Change from Baseline in at 20 weeks
Becks Depression Inventory for Youth
Time frame: Change from Baseline in at 30 weeks
Becks Depression Inventory for Youth
Time frame: Change from Baseline in at 40 weeks
The Risk-Taking and Self-Harm Inventory for adolescents (RTSHIA)
Time frame: Change from baseline at 40 weeks
The Risk-Taking and Self-Harm Inventory for adolescents (RTSHIA)
Time frame: change from baseline at 10 weeks
The Risk-Taking and Self-Harm Inventory for adolescents (RTSHIA)
Time frame: change from baseline at 20 weeks
The Risk-Taking and Self-Harm Inventory for adolescents (RTSHIA)
Time frame: Chage from baseline at 30 weeks
ZAN-BPD Zanarini Rating Scale for Borderline Personality Disorder
Time frame: Change from baseline at 40 weeks
The Health of the Nation Outcome Scale for Children and Adolescent (HoNOSCA)
Time frame: Change from baseline at 40 weeks
The Childrens' Global Assessment Scale (CGAS)
Time frame: Change from baseline at 40 weeks
The childhood behaviour checklist (CBCL, Parental outcome measure)
Time frame: Change from baseline at 40 weeks
The childhood behaviour checklist (CBCL, Parental outcome measure)
Time frame: Change from baseline at 10 weeks
The childhood behaviour checklist (CBCL, Parental outcome measure)
Time frame: Change from baseline at 20 weeks
The childhood behaviour checklist (CBCL, Parental outcome measure)
Time frame: Change from baseline at 30 weeks
The borderline personality feature scale for Children - parental version (BPFS-P)
Time frame: Change from baseline at 40 weeks
The borderline personality feature scale for Children - parental version (BPFS-P)
Time frame: Change from baseline at 10 weeks
The borderline personality feature scale for Children - parental version (BPFS-P)
Time frame: Change from baseline at 20 weeks
The borderline personality feature scale for Children - parental version (BPFS-P)
Time frame: Change from baseline at 30 weeks
Number of patients' hospital admissions and visits to the emergency room
Time frame: Change from baseline at 40 weeks
The Youth Self-Report (YSR)
Time frame: Change from baseline at 10 weeks
The Youth Self-Report (YSR)
Time frame: Change from baseline at 20 weeks
The Youth Self-Report (YSR)
Time frame: Change from baseline at 30 weeks
The Youth Self-Report (YSR)
Time frame: Change from baseline at 40 weeks
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