Evaluate the efficacy, Safety and Pharmacokinetics of Intravenous single injection LC28-0126 immediately before PCI (Percutaneous Coronary Intervention) in Patients with STEMI (ST-segment Elevation Myocardial Infarction)
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
Seoul National University Hospital
Seoul, South Korea
AUC of CK-MB for 72 hours post PCI
Time frame: pre PCI, PCI 0h, 6h, 12h, 18h, 24h, 48h, 72h
AUC of Troponin I and CK for 72h post PCI
Time frame: pre PCI, PCI 0h, 6h, 12h, 18h, 24h, 48h, 72h
Infarct size and myocardial function assessed by CMR and Echocardiogram
Time frame: Day 4, 30
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LC28-0126 Dose C