Clinical Evaluation, Biomarkers and Metabolomics of Sarcopenia in Frail Older Adults at Ambulatory Clinics

N/AUnknownNCT02073370

National Taiwan University Hospital350 enrolled

Overview

Sarcopenia related mobility dysfunction was a preventable presentation in transitional variation of frailty. However, the definition, associated risk factors, clinical course and outcome of sarcopenia in Taiwanese older adults are still under-clarified and need for further study.

Study Type

OBSERVATIONAL

Enrollment

350

Conditions

Frailty Sarcopenia

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * functional decline in recent one year * cognitive impairment * depressive symptom * mobility impairment * fall in recent one year * eating or feeding problems * weight loss * co-morbid conditions≧5 * tracking by different physician ≧3 in recent half year * poly-pharmacy≧8 in recent 3 months * hospitalization ≧1 in recent one year * emergency visits≧2 in recent one year * aged ≧ 80. Exclusion Criteria: * non-ambulatory (bed-ridden) patients * long-term residents at nursing homes * patients with a life expectancy shorter than six months * impairment in vision, hearing, or communicative ability, making convenience of clinical evaluation during the study period impossible.

Locations (1)

National Taiwan University Hospital

Taipei, Taiwan

Outcomes

Primary Outcomes

Domestic operation tool of sarcopenia for older adults

Young health adults are recruited for measurement of body composition using bio impedance analysis in order to establish the norm of skeletal muscle index

Time frame: Baseline

Secondary Outcomes

Change from baseline in body composition during aging

Using anthropometric measurements, and bio impedance analysis, the change in body composition are measured in the recruited older adults

Time frame: up to 2 years

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.