The purpose of the study is to evaluate the effect of MealShape, a Ceylon cinnamon extract (Cinnamomum zeylanicum) on blood glucose and insulin response after consumption of a standard meal composed of white bread, in healthy male and female volunteers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
18
Acute administration of 1 g PO (2 capsules of 500 mg)
Acute administration of 1 g PO (2 capsules of 500 mg)
Centre de Nutrition Clinique Naturalpha
Lilles, France
Blood glucose incremental Area Under the Curve between 0 and 120 minutes after consumption of a standard meal, compared between MealShape and the placebo
Time frame: Over 120 minutes after the consumption of a standard meal
Blood glucose incremental Area Under the Curve between 0 and 60 minutes compared between MealShape and the placebo after consumption of a standard meal,
Time frame: Over 60 minutes after consumption of a standard meal
Capillary blood glucose maximal concentration between MealShape and Placebo after consumption of a standard meal
Time frame: Over 120 minutes after consumption of a standard meal
Comparison of glycemia values between MealShape and Placebo at the following time points: T0, T15, T30, T45, T60, T90 and T120 minutes after consumption of a standard meal
Time frame: Over 120 minutes after consumption of a standard meal
Evaluation of the safety of MealShape with adverse events recording
Time frame: 3 weeks
Insulin incremental Area under the Curve between 0 and 120 minutes compared between MealShape and Placebo after consumption of a standard meal
Time frame: Over 120 minutes after consumption of a standard meal
Insulin incremental Area under the Curve between 0 and 60 minutes compared between MealShape and Placebo after consumption of a standard meal
Time frame: Over 60 minutes after connsumption of a standard meal
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