Study to Compare the Safety and Efficacy of Tacrolimus and Steroids in Combination With Mycophenolate Mofetil or Without Mycophenolate Mofetil in Liver Transplantation with Hepatitis B Virus(HBsAg) Positive
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
170
experimental group receive Tacrolimus as a main immunosuppressants and assistant is My-rept capsule®(Mycophenolate Mofetil),
control group receive same immunosuppressants except for My-rept capsule®(Mycophenolate Mofetil- investigational product
Asan Medical Center
Seoul, Korea, South Korea
RECRUITINGrejection
• Incidence rate has been confirmed acute cellular rejection(RAI 4 and over) from liver biopsy
Time frame: within 6months
rate of HBV
• Recurrence rate of HBV after liver transplantation for 24 weeks (HBsAg Positve)
Time frame: within 6 months
Graft survival rate
• Patients survival rate after liver transplantation for 24 weeks / Graft survival rate
Time frame: within 6 months
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