Metabolic Syndrome Cohort in Korea

N/AWithdrawnNCT02077530

Korea University Anam Hospital

Overview

Patients with metabolic syndrome living in Seoul area are included in this prospective registry for more than 10 years. All enrolled patients undergo thorough medical history survey. Enrolled patients will have coronary CT, 2D echocardiogram, treadmill test, pulse wave velocity, augmentation index, carotid intima-media thickness, and abdominal fat mass evaluation. Moreover, lipid profiles and inflammatory markers such as hsCRP, IL-6, TNF-alpha, VCAM-1, ICAM-1, adiponectin, MMP-9 will be measured. All participants will repeat the test and survey every year in Korea University Hospital.

Study Type

OBSERVATIONAL

Conditions

Metabolic Syndrome

Eligibility

Sex: ALLMin age: 30 YearsMax age: 64 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 3 out of 5 criteria * Central obesity: Men ≥ 90 cm Women ≥ 85 cm * Plasma triglycerides ≥ 150 mg/dL * HDL cholesterol Men \< 40 mg/dL, Women \< 50 mg/dL * Blood pressure ≥130/85 mm Hg (or treatment for hypertension) * Fasting plasma glucose ≥ 100 mg/dL * Age between 30 to 64 * Consent to our registry protocol Exclusion Criteria: * Patients who could not undergo coronary CT, 2D echocardiogram, treadmill test, and pulse wave velocity.

Locations (1)

Korea University Anam Hospital Metabolic Syndrome Research Center

Seoul, South Korea

Outcomes

Primary Outcomes

Cardiovascular events

Cardiovascular events such as fatal and non-fatal myocardial infarction, heart failure, need for coronary and peripheral revascularization, stroke, all-cause death, and cardiac death.

Time frame: 10 years

Data from ClinicalTrials.gov

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