Clinical, prospective and monocentric study aiming at assessing the feasibility of fibrosis detection and quantification (and of function assessment) during MRI without breath-holds in a population of adults and children with Duchenne myopathy.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
22
Service de médecin nucléaire / CHU Nancy Brabois
Vandœuvre-lès-Nancy, France
Number of exams correctly acquired (feasabiliy of the exam)
Was it possible to acquire the whole examination for every patient ?
Time frame: after the last inclusion
Number of exams allowing a qualitative assessment of images by the physician
The image quality allows a qualitative diagnosis ?
Time frame: after the last MRI exam
Number of exams allowing a quantitative assessment of the diagnosis
Did the image quality allow a quantitative assessment of the diagnosis ?
Time frame: after the last MRI examination
Number of anatomic cardiac segments with significant fibrosis according to the assessment methods (conventional LGE, qualitative detection with GRICS, and quantiative measure with GRICS)
correlation between fibrosis information (conventional LGE, qualitative detection with GRICS, and quantiative measure with GRICS)
Time frame: after the last inclusion
Number of cardiac segments with fibrosis and/or regional dysfunction
Correlation between fibrosis and regional function for each cardiac segment
Time frame: after the last inclusion
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.