Assessment of Blood Pressure Control and Target Organ Damage in Patients With Chronic Kidney Disease and Hypertension -II

Inclusion Criteria: 1. with informed consent 2. 20 \<= age \< 75 years 3. diagnosed as hypertension 6 months (or 3 visits) prior to enrollment, taking anti-hypertensive drugs over 3 months 4. all-cause chronic kidney disease patients with 15 \<= estimated GFR \< 90 5. no change of anti-hypertensive drugs within 2 weeks and good compliance Exclusion Criteria: 1. changed prescription according to ambulatory blood pressure monitoring (ABPM) regularly 2. had acute kidney injury/hospitalization 3. had a proteinuria of \> 6 g/day (spot urine protein to creatinine ratio \> 6.0 g/g Cr) 4. had end stage renal disease (ESRD) with dialysis and/or were a kidney recipient 5. had diseases, such as uncontrolled arrhythmia, uncontrolled bronchial asthma/chronic obstructive pulmonary disease, or primary endocrinologic diseases except diabetes mellitus 6. were pregnant/lactating women 7. were night shift workers.