Study to Assess the Efficacy and Safety of SKI3246 in Subjects With Non-Constipation Irritable Bowel Syndrome

Inclusion Criteria: * Have been diagnosed as non-constipation by ROME III. * Patients who voluntarily signed written informed consent may participate in the study. Exclusion Criteria: * Pregnant or lactating female. * Patients with a history of inflammatory bowel disease. * Severe neurological or psychological disease * History of allergic reaction to the medications used in this study * Use of other investigational drugs within 30 days prior to the study. * Patients that investigators consider ineligible for this study