Moxibustion for Mild and Moderate Ulcerative Colitis

N/ACompletedNCT02084186

Shanghai Institute of Acupuncture, Moxibustion and Meridian60 enrolled

Overview

The purpose of this study is to determine whether moxibustion is effective to mild and moderate ulcerative colitis and the effect of moxibustion on metabolism.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Ulcerative Colitis

Interventions

herb-partitioned moxibustionOTHER

Ignited moxa cones are placed upon herbal cake. Herbs are smashed into powder. Every 2.8g medicine powder mix with 3g millet wine and then be pressed into herbal cakes which are 28mm in diameter and 7mm in high with a specific mould. Then the herbal cake with a moxa cone will be fixed on Tianshu and Shangjuxu.

bran-partitioned moxibustionOTHER

Ignited moxa cones are placed upon bran cake. Every 2.8g bran powder mix with 3g millet wine and then be pressed into bran cakes which are 28mm in diameter and 7mm in high with a specific mould. Then the bran cake with a moxa cone will be fixed on Tianshu and Shangjuxu.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Meet the diagnosis of UC * Mayo ≤10 * Patients should have never received any pharmacological therapy or if they are receiving aminosalicylates and/or prednisolone (the dosage has been taken at least 4 weeks, and should be kept the same as before throughout the trial) * Patients should have never received antibiotic, biologicals, probiotics, acetaminophen, acetamide and contraceptive. * A written informed consent Exclusion Criteria: * Patients with cardiac, encephalic, hepatic, nephric, hematopoietic system, psychotic or any other serious diseases * Pregnancy or lactation

Locations (1)

Shanghai Institute of Acupuncture-Moxibustion and Meridian

Shanghai, China

Outcomes

Primary Outcomes

disease activity index (DAI)

Using Mayo subscore

Time frame: 3 months

Secondary Outcomes

Inflammatory Bowel Disease Questionnaire (IBDQ)

Time frame: 3 months

symptom score

Time frame: 3 months

histomorphology observation of intestinal mucosa

Using the Geboes histology score

Time frame: 3 months

metabolic profile of intestinal mucosa, urine, plasma and serum

Time frame: 3 months

Data from ClinicalTrials.gov

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