The purpose of this study is to determine which of the following drugs: enoxaparin, dabigatran and rivaroxaban causes least blood loss after total hip replacement (THR).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
60
Prof. A. Gruca Teaching Hospital, The Medical Centre of Postgraduate Education
Otwock, Woj. Mazowieckie, Poland
RECRUITINGTotal blood loss by the 3rd postoperative day
Measured for each individual. Measured according to the formula described by Nadler, Hidalgo and Bloch (Prediction of blood volume in normal human adults. Surgery 1962;51:224-32).
Time frame: 3rd day postoperatively
Drop in the haemoglobin value between 3rd day postop and preoperative
Difference between haemoglobin on the 3rd postopertive day and day before operation
Time frame: 3rd day postopertively
Wound healing disturbances according to the definition of Centers for Disease Control and Prevention
Wound healing disturbances - diagnosis to be made according to the definition of Centers for Disease Control and Prevention (Mangram, Horan, Pearson, Silver and Jarvis. Guideline for prevention of surgical site infection, 1999. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol. 1999 Apr;20(4):250-78)
Time frame: 3 months postoperatively
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