Bioequivalence of Fresenius Kabi USA, LLC Glucagon for SC Injection Compared to Glucagon for Injection (Bedford Laboratories)

Inclusion Criteria: 1. Males and females, 18 years or older, with a body mass index (BMI) of 18- 30 kg/m2 inclusive. 2. Good health as determined by lack of clinically significant abnormalities in health assessments performed at screening. 3. Signed and dated informed consent form, which meets all criteria of current guidelines of the Medical Research Council (MRC) of Canada and FDA regulations. 4. If female and of child bearing potential prepared to abstain from sexual intercourse, use a reliable non-hormonal method of contraception during the study (e.g. condom with spermicide, IUD). Females using hormonal contraceptives must have used the same method for at least 28 days prior and throughout the study. Exclusion Criteria: 1. If female, pregnant, lactating or likely to become pregnant during the study. 2. History of allergy or sensitivity to glucagon or history of any drug hypersensitivity or intolerance which, in the opinion of the Investigator, would compromise the safety of the subject or the study. 3. Significant history or current evidence of chronic infectious disease, system disorders or organ dysfunction. 4. Presence of gastrointestinal disease or history of malabsorption within the last year. Any history of duodenal or gastric ulcer. 5. History of psychiatric disorders occurring within the last two years that required hospitalization medication. 6. Presence of a medical condition requiring regular treatment with prescription drugs. 7. Use of any drugs known to induce or inhibit hepatic drug metabolism (examples of inducers: barbiturates, carbamazepine, phenytoin, glucocorticoids, omeprazole; examples of inhibitors: antidepressants (SSRI), cimetidine, diltiazem, macrolides, imidazoles, neuroleptics, verapamil, fluoroquinolones, antihistamines) within 30 days prior to administration of the study medication. 8. Receipt of any drug as part of a research study within 30 days prior to dosing. 9. Drug or alcohol addiction requiring treatment in the past 12 months. 10. Donation or significant loss of whole blood (480 ml or more) within 3 months or plasma within 14 days prior to dosing. 11. Positive test results for HIV, Hepatitis B surface antigen or Hepatitis C antibody. 12. Unable, or unwilling to tolerate multiple venipunctures. 13. Has difficulty fasting or consuming the standard meals that will be provided. 14. No prescription medications (other than contraceptives) used within 14 days prior to initial study dosing and throughout the times of sample collection each period. 15. No over-the-counter medications within 14 days prior to each dosing and throughout the times of sample collection each period. 16. No alcohol, caffeine/xanthine or grapefruit containing food or beverages (e.g. chocolate, coffee, tea, cola, Fresca®) ingested within 3 days prior to each dosing and throughout the times of sample collection each period. 17. All subjects will have a saliva/urine test for drugs of abuse at check- in each study period. Subjects with positive results will be withdrawn from the study. 18. All female subjects will be screened for pregnancy at check-in each study period with a urine pregnancy test. Subjects with positive results will be withdrawn from the study.