Electro-acupuncture and Transcorneal Electrical Stimulation (TES) for Retinitis Pigmentosa

N/AActive Not RecruitingNCT02086890

Nova Southeastern University21 enrolled

Overview

Measures of vision in RP patients receiving promising therapy using transcorneal electrical stimulation.

Retinitis pigmentosa (RP) is a slowly progressive retinal degeneration for which there is no proven treatment. Patients are interested in trying alternative therapies to try to reduce their vision loss, but only limited research evidence exists to support their use and potential benefit. The goal of this research project is to gain a better understanding of possible changes in ocular and retinal blood flow and measures of vision in RP patients receiving two promising therapies, electroacupuncture and transcorneal electrical stimulation. We are currently only doing transcorneal electrical stimulation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Retinitis Pigmentosa

Interventions

Electro-acupunctureDEVICE

Laser AcupunctureDEVICE

Transcorneal Electrical StimulationDEVICE

Sham Electro-acupunctureDEVICE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18+ * Diagnosis of retinitis pigmentosa (RP) * Best-corrected visual acuity better than 20/400 in at least one eye * More than 20% loss of Goldmann Visual Field area (III4e test target) in at least one eye * Able and willing to participate in all study visits for a \~4-6 month period * Provide informed consent Exclusion Criteria: * Very severe vision losses in both eyes (e.g., hand motions or light perception only) with difficulty performing the proposed vision tests * Vision loss due to ocular diseases other than RP, cystoid macular edema, or cataracts * Schedules do not permit participation in all study visits * Previous acupuncture or TES treatment for RP * Inability to understand study procedures or communicate responses to visual stimuli in a consistent manner (cognitive impairment) * Dementia; Long or short-term memory loss * Unable to read or speak English * Smoking, excessive alcohol, or illegal drug use * Receiving current psychiatric care (i.e. unstable emotional and mental health status) * History of excessive bleeding * Reduced general health and/or systemic medications that may diminish the potential response to the electroacupuncture treatments * Implanted cardiac pacemaker * Pregnancy

Locations (1)

Nova Southeastern University; College of Optometry

Fort Lauderdale, Florida, United States