This is a 12 month non-interventional study with solifenacin succinate, evaluating the effect of solifenacin on quality of life (QoL) of patients previously treated with antimuscarinics (Males and Females with Overactive Bladder (OAB) symptoms withdrawing their treatment with antimuscarinics because of safety and/or efficacy reasons) - measured by Perception of Treatment Satisfaction (TS-VAS) and to evaluate the effect of solifenacin on quality of life measured by Over Active Bladder-q Short Form (OAB-q SF), EuroQol Group scoring system (EQ-5D-5L).
Study Type
OBSERVATIONAL
Enrollment
2,000
Patients with residual OAB symptoms (urge urinary incontinence, urgency, and frequency) after treatment with other antimuscarinics
Site CZ42003 Private Practice
Benešov, Czechia
Site CZ42001 Private Practice
Beroun, Czechia
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Blansko, Czechia
Site CZ42023 Private Practice
Boskovice, Czechia
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Brno, Czechia
Site CZ42034 Hospital
Change from baseline of Over Active Bladder questionnaire Short Form (OAB-q SF) score
Time frame: baseline, month 6 and 12
Change from baseline of Patient Assessment of Treatment Satisfaction (TS-VAS)
Time frame: baseline, month 6 and 12
Change from baseline in EuroQol Group system (EQ-5D-5L) score
Time frame: baseline, month 6 and 12
Change in QoL according to previous antimuscarinic treatment and sex (assessed by: TS-VAS score, OAB-q SF score, EQ-5D-5L)
Time frame: baseline, month 1, 3, 6 and 12
Change from baseline in OAB symptoms assessed by micturition diary
Mean number of urgency episode per 24 hours, mean number of micturition per 24 hours, mean number of nocturia episodes per 24 hours, mean number of urge incontinence (UUI) episodes per week
Time frame: baseline, month 1, 3, 6 and 12
Persistence to therapy (measured by proportion of Days Covered (PDC, threshold of 80 percent during the measurement period), median length of therapy (days))
Time frame: 12 months
Occurence of adverse drug reaction
Time frame: 12 months
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Brno, Czechia
Site CZ42035 Private Practice
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